SYMPHYTUM OFFICINALE SKIN SAFETY SKIN
Topical preparations that contain comfrey extract may have a great application in the treatment of skin irritation.Īllantoin anti-irritant potential comfrey extract proliferation viability. Our results indicate that the biological activity of the comfrey root extract cannot be attributed only to allantoin but is also likely the result of the interaction of different compounds present in AECR. Creams showed better effect on hydration and EI compared with the gels that contained the same components. Pharmaceutical preparations that contained AECR showed better anti-irritant potential compared with PA. Aqueous extract of the comfrey root effect on cell proliferation in concentrations higher than 40 µg/ml was significantly stimulatory for L929 but inhibitory for MDCK cells. Pure allantoin showed mild inhibitory effect on proliferation of both cell lines at concentrations 40 and 100 µg/ml, but more pronounced on MDCK cells. Anti-irritant potential was determined by measuring electrical capacitance, erythema index (EI) and transepidermal water loss of artificially irritated skin of young healthy volunteers, 3 and 7 days after application of creams and gels with PA or AECR. Cell viability and proliferation of epithelial (MDCK) and fibroblastic (L929) cell line were studied by using MTT test.
SYMPHYTUM OFFICINALE SKIN SAFETY TRIAL
Combination of Comfrey Root Extract Plus Methyl Nicotinate in Patients with Conditions of Acute Upper or Low Back Pain: A Multicentre Randomised Controlled Trial.Topical symphytum herb concentrate cream against myalgia: a randomized controlled double-blind clinical study.Efficacy and safety of comfrey root extract ointment in the treatment of acute upper or lower back pain: results of a double-blind randomised placebo controlled multicentre trial.Comfrey root: from tradition to modern clinical trials.Efficacy and safety of symphytum herb extract cream in the treatment of pressure ulcers.Comparative Study of the Biological Activity of Allantoin and Aqueous Extract of the Comfrey Root.Comfrey is found in many products including herbal teas, skin creams, pills, capsules.
Efficacy and Safety of an Anti-aging Technology for the Treatment of Facial Wrinkles and Skin Moisturization Historically comfrey was felt to help heal broken bones and.
An investigation into multifaceted mechanisms of action of allantoin in wound healing.Tolerability and effectiveness of an antitrauma cream with comfrey herb extract in pediatric use with application on intact and on broken skin.Epidermal Regeneration Induced by Comfrey Extract: A Study by Light and Electron Microscopy.Wound healing effects of a Symphytum herb extract cream (Symphytum x uplandicum NYMAN: ): results of a randomized controlled double-blind study.Profile of wound healing process induced by allantoin.Articles on StyleCraze are backed by verified information from peer-reviewed and academic research papers, reputed organizations, research institutions, and medical associations to ensure accuracy and relevance.
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